Unpad Graduate School Develops Polymethylhydrosiloxane as a Potential Vitreous Humor Substitute
Widy
UNPAD Staff Writer




Researchers from the Graduate School, Universitas Padjadjaran, have synthesized and characterized polymethylhydrosiloxane (PMHS) as a potential alternative material for vitreous humor substitution in ophthalmological procedures. The synthesis involved a two-step process: hydrolysis to produce short-chain PMHS and condensation to produce long-chain PMHS, using dichloromethylsilane (DCHS) as a precursor and dichloromethane (DCM) as a solvent. The polymerization process was accelerated by heating and assisted by potassium hydroxide (KOH). Characterization techniques such as FTIR and NMR spectroscopy confirmed the successful synthesis of PMHS, with the long-chain PMHS exhibiting properties suitable for vitreous substitution.
This research contributes to the Sustainable Development Goals (SDGs) by:
SDG 3 (Good Health and Well-being): Providing an alternative material for vitreous humor substitution, potentially improving outcomes in retinal surgeries.
SDG 9 (Industry, Innovation, and Infrastructure): Advancing material science and innovation in medical applications.
SDG 12 (Responsible Consumption and Production): Utilizing locally sourced materials and processes to reduce reliance on imported medical supplies.
The development of PMHS as a vitreous humor substitute offers a promising avenue for enhancing ophthalmological treatments, aligning with sustainable development goals in healthcare and innovation.
https://link-springer-com.unpad.idm.oclc.org/article/10.1007/s10965-024-04128-8: Unpad Graduate School Develops Polymethylhydrosiloxane as a Potential Vitreous Humor Substitute