Researcher from the Graduate School, Universitas Padjadjaran, led by Zidni Muflikhati together with other co-authors, have pioneered the development of highly specific molecular markers for Typhonium flagelliforme (rodent tuber) as potential anticancer therapeutics. By targeting the lectin gene, their study identified key Single Nucleotide Polymorphisms (SNPs) at around 500 base pairs — specifically, a silent mutation at 113 bp and a missense mutation at 241 bp. The team designed two marker systems: a SNAP marker (Lec113) for rapid screening using a three-primer assay, and an ARMS marker (Lec241) with high selectivity. Both demonstrated robust specificity and sensitivity in discriminating mutant lines from wild-type plants, ultimately enabling faster and more accurate selection of high-anticancer–potential varieties.

This breakthrough contributes significantly to advancing several Sustainable Development Goals (SDGs). First, it supports SDG 3 (Good Health and Well-Being) by enabling the development of plant-based anticancer resources with greater precision and efficiency. Second, it aligns with SDG 9 (Industry, Innovation, and Infrastructure) through the application of cutting-edge, cost-effective molecular tools in crop breeding. Finally, it advances SDG 12 (Responsible Consumption and Production) by streamlining the breeding process for valuable medicinal plants, reducing waste and promoting targeted resource utilization.