A team of researchers from the Graduate School, Universitas Padjadjaran—led by Sriati Wahyudi, Ayi Bahtiar, and Camellia Panatarani, along with Anas Anas—has introduced an innovative aptasensor leveraging carbon nanodots (CNDs) to detect organophosphorus pesticide residues with ultra-high sensitivity. Utilizing a fluorescence resonance energy transfer (FRET) mechanism involving CNDs, gold nanoparticles (AuNPs), and specific aptamers, the sensor switches from a quenched to a fluorescing state when pesticides like diazinon bind, enabling detection down to nanomolar concentrations. The method boasts high selectivity, ease of use, non-cytotoxicity, and affordability, marking a substantial advance for food safety monitoring. This groundbreaking nano-sensing platform directly contributes to key Sustainable Development Goals. It strengthens SDG 2 (Zero Hunger) by safeguarding food from harmful residues; supports SDG 3 (Good Health and Well-being) by enabling rapid detection of toxins; and aligns with SDG 12 (Responsible Consumption and Production) by promoting safer agricultural practices. Its low-cost, user-friendly design also helps empower small-scale producers and communities, reinforcing SDG 9 (Industry, Innovation and Infrastructure) through accessible technological innovation.